1996
unpasteurized apple juice outbreak:
14 children with kidney failure
syndrome, 1 death
21
juice outbreaks reported
to CDC, 1995–2005
<9%
vitamin C loss across heat and
non-heat treatments of orange
juice in one study

Some health writers argue that pasteurized juice is a waste of money because heat destroys vitamins, enzymes, and flavor, leaving little more than sugar water, and that fresh, unpasteurized or cold-pressed juice is the only kind worth drinking. Juice bars and premium brands have built a market around this idea. On the other side, food safety officials point to outbreaks traced to unpasteurized juice, including one in 1996 that sickened dozens of people and killed a toddler, which led to federal rules requiring juice makers to reduce pathogens.

This article examines what pasteurization does to juice, what outbreaks show about the risks of untreated juice, how newer methods such as high-pressure processing work, and whether juice of any kind is a good use of money compared with whole fruits and vegetables.

Key takeaways

In 1996, unpasteurized apple juice from a major brand caused an E. coli O157:H7 outbreak in which 70 people were infected, 25 hospitalized, 14 developed hemolytic uremic syndrome, and one child died. CDC data show 21 juice-associated outbreaks with 1,366 illnesses from 1995 to 2005.

Federal juice HACCP rules, phased in from 2002 to 2004, require juice processors to reduce pathogens; unpasteurized packaged juice must carry a warning label, and outbreaks declined after implementation.

Pasteurization causes modest nutrient losses. In one study of orange juice, vitamin C losses were under 9 percent across high-pressure, pulsed electric field, and heat treatments, with higher temperatures causing somewhat greater losses.

High-pressure processing (HPP), used for many “cold-pressed” juices, reduces pathogens without heat and is accepted as an alternative to pasteurization. Whole fruits and vegetables offer more fiber and are generally a better nutritional choice than any juice.

The Outbreak That Changed Juice Rules

In October 1996, an outbreak of E. coli O157:H7 was traced to unpasteurized apple juice from a well-known brand that marketed its juices as fresh and natural. A 1999 investigation published in the Annals of Internal Medicine by Stephen Cody and colleagues identified 70 people with E. coli O157:H7 infection who had drunk the juice; 25 were hospitalized, 14 developed hemolytic uremic syndrome, a cause of kidney failure, and one child died. The researchers found that standard procedures at a state-of-the-art plant were inadequate to eliminate contamination and concluded that unpasteurized juices must be considered potentially hazardous foods. The outbreak led to widespread changes in the juice industry.

Apples can be contaminated by animal feces in orchards, particularly fallen fruit, and E. coli O157:H7 can survive in acidic juice. Other outbreaks have been linked to unpasteurized orange juice contaminated with Salmonella and to cider contaminated with Cryptosporidium.

What the Outbreak Data Show

A 2008 analysis in the Journal of Food Protection by Julie Vojdani, Larry Beuchat, and Robert Tauxe reviewed juice-associated outbreaks reported to the CDC from 1995 through 2005. There were 21 outbreaks: 10 involving apple juice or cider, 8 orange juice, and 3 other juices, causing 1,366 illnesses. Among outbreaks with known causes, Salmonella and E. coli O157:H7 each caused five, Cryptosporidium two, and other pathogens the rest. Most implicated juices were unpasteurized. The authors noted that the FDA’s juice regulation, which took effect in 2002, 2003, or 2004 depending on business size, requires juice processors to follow a hazard analysis and critical control point (HACCP) plan, and that fewer juice-associated outbreaks were reported after the regulation was implemented.

U.S. Juice-Associated Outbreaks by Juice Type, 1995–2005 10Apple juice/cider 8Orange juice 3Other juices 21 outbreaks, 1,366 illnesses. Source: Vojdani JD, Beuchat LR, Tauxe RV. J Food Prot (2008).

Current Rules and Warning Labels

Under the FDA’s juice HACCP regulation, processors must identify hazards and use processes that achieve a 5-log, or 100,000-fold, reduction in the most resistant pathogen of concern. This can be accomplished through heat pasteurization or through validated non-heat methods such as high-pressure processing or ultraviolet treatment. The FDA explains that most juice sold in the United States is pasteurized or treated, but some grocery stores, health food stores, cider mills, farmers markets, and juice bars sell packaged juice made on site that has not been treated; such packaged products must carry a warning that the product has not been pasteurized and may contain harmful bacteria that can cause serious illness in children, the elderly, and people with weakened immune systems. Juice sold by the glass, such as at juice bars and restaurants, does not require a warning label.

What Pasteurization Does to Nutrients

Heat pasteurization of juice typically involves heating to around 70 to 90°C for seconds to a minute, followed by rapid cooling. Heat-sensitive nutrients, particularly vitamin C and some aroma compounds, can decline, and the degree depends on temperature, time, and storage. A 2005 study in the Journal of Agricultural and Food Chemistry by Concepción Sánchez-Moreno and colleagues compared orange juice treated with high pressure, pulsed electric fields, low and high heat pasteurization, and freezing. Losses of total vitamin C were under 9 percent across treatments, though higher temperatures tended to cause larger decreases. Carotenoids and flavonoids were also affected modestly, with some differences between methods.

Storage time often matters more than processing method. Vitamin C in juice declines during storage, especially after opening, regardless of whether the juice was pasteurized. Fresh juice consumed immediately retains the most vitamin C, but unpasteurized juice stored for days loses vitamin C and allows any pathogens present to persist.

Claims that pasteurized juice is “dead” because enzymes are destroyed overlook that enzymes in food are proteins largely broken down during digestion, and the human body produces its own digestive enzymes. Heat can change flavor, which is a legitimate reason some people prefer fresh or high-pressure-processed juice.

Type of juice Pathogen reduction Nutrients and flavor
Heat-pasteurized Validated 5-log reduction Modest vitamin C loss; some flavor change
High-pressure processed (HPP) Validated 5-log reduction without heat Closer to fresh flavor; small nutrient losses
Fresh, unpasteurized (packaged) None; warning label required Highest vitamin C if consumed quickly
Fresh, made to order None; no label required Fresh flavor; risk depends on produce handling
General comparison based on FDA information and studies cited in this article.

High-Pressure Processing and “Cold-Pressed” Juice

Many premium juices labeled “cold-pressed” are bottled and then treated with high-pressure processing, in which sealed bottles are subjected to very high water pressure, around 400 to 600 megapascals, for a few minutes. This pressure inactivates many bacteria, yeasts, and molds without heat, extending shelf life and meeting FDA pathogen reduction requirements when validated. HPP juices often taste closer to fresh juice and retain more heat-sensitive compounds. They are more expensive than conventional pasteurized juice. “Cold-pressed” refers to how the juice was extracted, using a hydraulic press rather than a centrifugal juicer, not to whether it was treated for safety, so shoppers should read labels to see whether a cold-pressed juice was HPP-treated or is unpasteurized with a warning label.

Is Juice Worth the Money at All?

Whether pasteurized, HPP, or fresh, juice lacks most of the fiber found in whole fruits and vegetables and delivers sugars in a form that is quickly absorbed. A cup of orange juice contains roughly as much sugar as a cup of soda, though it also provides vitamin C, potassium, and folate. Dietary guidelines recommend that most fruit intake come from whole fruits, and the American Academy of Pediatrics advises limiting juice for children and avoiding it for infants under one year. Vegetable juices contain less sugar but also less fiber than whole vegetables. For most people, eating whole produce is both cheaper and more nutritious than buying premium juice.

Cider and Cryptosporidium

Apple cider pressed at farms and orchards has been linked to outbreaks of parasites as well as bacteria. A 1994 investigation in JAMA by Paul Millard and colleagues described an outbreak at an agricultural fair in Maine, where about 26 percent of surveyed attendees became ill after drinking fresh-pressed apple cider; Cryptosporidium oocysts were found in stool samples from most patients tested. The authors described it as the first large cryptosporidiosis outbreak with documented foodborne transmission and emphasized the need to prevent contamination of produce with farm animal waste. Cryptosporidium is resistant to chlorine and can cause prolonged diarrhea, particularly dangerous for people with weakened immune systems.

Juice, Whole Fruit, and Diabetes Risk

Beyond safety, research has compared juice with whole fruit for long-term health. A 2013 study in The BMJ by Isao Muraki and colleagues analyzed three large U.S. cohorts with more than 3.4 million person-years of follow-up. Greater consumption of certain whole fruits, particularly blueberries, grapes, and apples, was associated with lower risk of type 2 diabetes, whereas greater fruit juice consumption was associated with higher risk; each additional three servings per week of juice was associated with an 8 percent higher risk. The findings suggest that the fiber and structure of whole fruit, which slow sugar absorption, matter for health.

The American Academy of Pediatrics’ 2017 policy statement by Melvin Heyman and Steven Abrams recommends no juice for infants under 12 months, and limits for older children, noting that juice’s high sugar content contributes to excess calories and dental caries and that whole fruit is preferable. These recommendations apply whether juice is pasteurized, cold-pressed, or fresh.

Whole Fruit vs Fruit Juice and Type 2 Diabetes Risk Whole fruitsBlueberries, grapes, applesassociated with lower riskFiber slows sugar absorption Fruit juiceEach +3 servings/weekassociated with 8% higher riskHR 1.08 (1.05–1.11) Three U.S. cohorts, 3.4 million person-years. Source: Muraki I, et al. BMJ (2013).

Who Should Avoid Unpasteurized Juice

Children, older adults, pregnant people, and people with weakened immune systems are at greatest risk of severe illness from pathogens in untreated juice and should choose pasteurized or HPP-treated juice. Pregnant people should be especially cautious about Listeria and other pathogens. Healthy adults who choose fresh, unpasteurized juice can reduce risk by buying from businesses with strong food safety practices, ensuring produce is washed and that equipment is cleaned, and drinking juice promptly.

How Pathogens Get Into Juice

Fruits and vegetables can become contaminated in the field through irrigation water, manure, wildlife, and soil, and after harvest through handling, washing water, and equipment. Apples that fall to the ground, sometimes used for cider, are particularly vulnerable to contamination from animal droppings. Damaged or bruised fruit can harbor bacteria inside the flesh, where surface washing cannot reach. During juicing, contamination on the surface of a few fruits can be spread throughout a batch. Acidic juices such as apple and orange were once thought to be inhospitable to pathogens, but E. coli O157:H7 and Salmonella can survive for days in refrigerated acidic juice, and parasites such as Cryptosporidium are not affected by acidity.

Safe Juicing at Home

Making juice at home allows control over ingredients and freshness, but basic precautions reduce risk. Wash hands, produce, and equipment thoroughly; scrub firm produce under running water; cut away bruised or damaged areas; avoid using fallen fruit; clean juicers promptly after use, since residue can harbor bacteria; drink juice soon after making it, or refrigerate and consume within a day; and avoid giving unpasteurized homemade juice to infants, young children, pregnant people, older adults, or people with weakened immune systems. Bringing homemade juice or cider to a boil and cooling it can kill pathogens, though it changes flavor.

Reading Juice Labels

Labels provide clues about how juice was treated. “Pasteurized” indicates heat treatment. “High pressure processed,” “HPP,” or “cold pasteurized” indicates non-thermal treatment. A warning statement indicates the juice has not been treated to reduce pathogens. “100% juice” means no added sugars or other ingredients beyond juice, while “juice drink” or “cocktail” may contain added sugars and less actual juice. “Not from concentrate” means juice was not evaporated and reconstituted, but it may still be pasteurized and stored for long periods.

The Cost Question

Premium cold-pressed juices can cost several dollars or more per bottle, far more than pasteurized juice or the whole fruits and vegetables used to make them. For people who enjoy their taste, they can be an occasional treat, but they offer no proven health advantages that justify replacing whole produce. Spending the same money on a variety of fresh, frozen, or canned fruits and vegetables provides more fiber, fewer free sugars, and greater satiety. Juice cleanses marketed for detoxification lack scientific support; the liver and kidneys handle detoxification, and restrictive juice-only diets can cause low energy and may be unsafe for some people.

Juice Processing Technologies Compared

Several technologies can reduce pathogens in juice. Heat pasteurization remains the most common and least expensive. High-pressure processing uses pressure rather than heat and preserves fresh-like flavor. Ultraviolet light treatment can reduce pathogens in clear juices such as apple cider, though it is less effective in cloudy juices. Pulsed electric fields use short bursts of high voltage and are used commercially in some countries. Each method must be validated to achieve the required pathogen reduction for the specific juice. The choice affects cost, flavor, shelf life, and nutrient retention, which is why different products on store shelves use different methods.

Key Facts at a Glance

In 1996, unpasteurized apple juice caused an E. coli O157:H7 outbreak with 70 cases, 25 hospitalizations, 14 cases of hemolytic uremic syndrome, and one death. CDC recorded 21 juice outbreaks with 1,366 illnesses from 1995 to 2005, mostly from unpasteurized products, and fewer outbreaks after juice HACCP rules took effect in 2002 to 2004. Untreated packaged juice must carry a warning, but juice sold by the glass does not. One study found vitamin C losses under 9 percent across heat and non-heat treatments of orange juice. Fruit juice intake was associated with higher type 2 diabetes risk while certain whole fruits were associated with lower risk.

Common Myths

“Pasteurized juice has no nutrients.” It retains most vitamins and minerals, with modest losses of heat-sensitive compounds.

“Acidic juice can’t carry pathogens.” E. coli O157:H7, Salmonella, and Cryptosporidium have caused juice outbreaks.

“Cold-pressed means raw.” Many cold-pressed juices are treated with high pressure; check the label.

“Juice cleanses detoxify the body.” There is no evidence that juice cleanses remove toxins; the liver and kidneys perform this function.

Juice in Children’s Diets

Children are both the heaviest juice drinkers relative to body size and the most vulnerable to foodborne illness, which makes juice choices especially important for families. Pediatric guidance recommends no juice before 12 months; up to 4 ounces daily for toddlers aged 1 to 3; 4 to 6 ounces for ages 4 to 6; and up to 8 ounces for older children and teens, always as 100 percent juice and preferably with meals. Juice should not be given in bottles or sippy cups carried throughout the day, which prolongs teeth exposure to sugar. Only pasteurized or otherwise treated juice should be given to young children. Water and milk are the recommended primary drinks for children.

Vegetable Juices and Green Juices

Vegetable and green juices made from kale, spinach, celery, cucumber, and similar produce contain less sugar than fruit juices and provide vitamins, minerals, and plant compounds. However, juicing removes most fiber, and very large quantities of certain greens can be a concern for some people, such as those taking blood thinners like warfarin, which interacts with vitamin K, or people prone to kidney stones, who may need to limit high-oxalate greens such as spinach. Like fruit juices, green juices sold fresh at juice bars are often unpasteurized. Blended smoothies that retain fiber are a nutritionally preferable alternative to juicing for many people.

Celery Juice and Other Trends

Juice trends come and go on social media, with claims that drinking celery juice daily cures chronic illnesses or that juice cleanses reset the body. These claims are not supported by clinical evidence. Celery juice is low in calories and provides some potassium and vitamin K, but there is no evidence it cures disease. Evaluating trends by looking for controlled studies rather than testimonials helps avoid spending money on unproven claims.

Juice Bars and Food Safety

Juice bars that make juice to order are subject to local food safety codes, but because juice sold by the glass is exempt from warning labels, customers may not realize it is untreated. Good practices include washing and sanitizing produce, cleaning equipment frequently, keeping produce and juice refrigerated, and training staff in hygiene. Some juice bars choose to sell only HPP-treated bottled juices or post information about safety. Customers in higher-risk groups can ask whether juice is pasteurized or treated before buying.

Storage and Shelf Life

Different juices have very different shelf lives. Shelf-stable pasteurized juices in aseptic cartons or bottles can last months unopened. Refrigerated pasteurized juices typically last a few weeks unopened. HPP juices usually have refrigerated shelf lives of several weeks. Fresh unpasteurized juice should be consumed within a day or two. Once opened, all juices should be refrigerated and used within about a week, and any juice that smells off, fizzes unexpectedly, or has a swollen container should be discarded. Vitamin C content declines over storage time regardless of processing, so buying smaller quantities and consuming them promptly preserves nutritional value.

Questions to Ask When Buying Juice

Has this juice been pasteurized or treated with high pressure? Is it 100 percent juice, or does it contain added sugars? How long has it been stored, and when does it expire? Is it appropriate for the people in my household, including young children or anyone pregnant or immunocompromised? Would whole fruit or vegetables serve the same purpose at lower cost? Answering these questions helps shoppers choose juice that fits their needs and safety requirements.

Key Terms

Pasteurization: Heat treatment to reduce pathogens.

High-pressure processing (HPP): A non-thermal method using pressure to inactivate microorganisms.

Juice HACCP: The FDA rule requiring juice processors to control hazards and reduce pathogens.

5-log reduction: A 100,000-fold reduction in the most resistant pathogen of concern.

Hemolytic uremic syndrome: A serious complication of certain E. coli infections causing kidney failure.

The Bottom Line

Pasteurization causes modest nutrient losses, mainly of heat-sensitive vitamin C and aroma compounds, while sharply reducing the risk of dangerous pathogens that have caused juice outbreaks, including a 1996 outbreak in which a child died. Juice HACCP rules and warning labels have reduced outbreaks. High-pressure processing offers a fresh-tasting alternative that still meets safety standards. Unpasteurized juice carries real risks, especially for children, pregnant people, older adults, and the immunocompromised. Most importantly, whole fruits and vegetables are a better nutritional choice than any juice, providing fiber and lower diabetes risk at a lower cost.

Further Reading

The FDA’s juice safety and HACCP pages explain regulations and warning labels. The American Academy of Pediatrics provides guidance on juice for children. Peer-reviewed studies cited here describe outbreaks, nutrient effects of processing, and links between juice, whole fruit, and diabetes risk.

Pregnancy and Juice Safety

Pregnant people are advised to avoid unpasteurized juice and cider because infections such as Listeria, Salmonella, and E. coli can cause severe illness and, in the case of Listeria, may lead to miscarriage, stillbirth, or infection of the newborn. Pasteurized and HPP-treated juices are considered safe during pregnancy. When dining out, asking whether fresh juice is pasteurized helps avoid unintentional exposure. Pregnant people can also meet vitamin C and other nutrient needs through whole fruits and vegetables, which provide fiber that supports digestive health during pregnancy.

A Practical Approach

For most households, a practical approach is to rely mainly on whole fruits and vegetables, use 100 percent pasteurized or HPP juice in modest amounts when desired, and reserve fresh, unpasteurized juice for healthy adults who understand the small but real risk. Families with young children, pregnant members, older adults, or anyone with a weakened immune system should choose treated juice. Paying a premium for cold-pressed juice is a matter of taste rather than health, and the money may be better spent on a wider variety of produce. These simple guidelines balance enjoyment, nutrition, safety, and cost.

Looking Ahead

Juice processing continues to evolve, with new non-thermal technologies, improved validation methods, and growing demand for minimally processed products. Regulators continue to monitor outbreaks, and food safety research examines emerging risks such as pathogens adapted to acidic conditions. Consumers can expect more variety in treated juices that taste fresh while meeting safety standards. Whatever the technology, the basic advice remains the same: choose treated juice for vulnerable people, enjoy juice in moderation, and favor whole produce for everyday nutrition.

A Balanced View

Claims that pasteurized juice is worthless overstate nutrient losses, while dismissing all concerns about processing ignores real differences in flavor and some heat-sensitive compounds. The most important differences are safety and fiber: treated juice greatly reduces the risk of serious infection, and whole produce outperforms any juice nutritionally. Personal preferences about taste and price can guide choices among treated juices, while safety considerations should guide choices for vulnerable people. Viewed this way, the juice debate becomes less about pasteurization itself and more about how juice fits into an overall healthy diet built on whole fruits and vegetables.

Families can put these principles into practice by keeping a bowl of whole fruit within easy reach, serving water and milk as everyday drinks for children, and treating juice, whether pasteurized, high-pressure processed, or freshly squeezed, as an occasional addition rather than a daily staple or a replacement for eating fruits and vegetables.

Schools, child care centers, and summer programs can apply the same guidance by serving water, milk, and whole fruit rather than juice, and by choosing only pasteurized or otherwise treated juice when juice is offered, protecting young children who are most vulnerable to foodborne illness.

Small changes like these add up over time, improving children’s diets while keeping them safe from preventable infections and building healthy habits that can last into adulthood.

Parents who are unsure whether a juice is safe for their child can check the label for a pasteurization or high-pressure processing statement, or simply choose whole fruit instead.

Frequently Asked Questions

Does pasteurization destroy the nutrients in juice?

It causes modest losses of heat-sensitive nutrients like vitamin C; one study found total vitamin C losses under 9 percent across processing methods.

Is cold-pressed juice pasteurized?

Not by heat, but many cold-pressed juices are treated with high-pressure processing to kill pathogens. Unpasteurized packaged juice must carry a warning label.

Why is unpasteurized juice risky?

Produce can carry pathogens like E. coli O157:H7 and Salmonella, which have caused outbreaks linked to unpasteurized juice.

Do juice bars have to warn customers?

No. Juice sold by the glass does not require a warning label.

Is juice healthier than whole fruit?

No. Whole fruit provides fiber and is generally the better choice.

References

  1. Cody SH, Glynn MK, Farrar JA, et al. An outbreak of Escherichia coli O157:H7 infection from unpasteurized commercial apple juice. Annals of Internal Medicine. 1999;130(3):202–209. PMID 10049198
  2. Vojdani JD, Beuchat LR, Tauxe RV. Juice-associated outbreaks of human illness in the United States, 1995 through 2005. Journal of Food Protection. 2008;71(2):356–364. PMID 18326187
  3. Sánchez-Moreno C, Plaza L, Elez-Martínez P, et al. Impact of high pressure and pulsed electric fields on bioactive compounds and antioxidant activity of orange juice in comparison with traditional thermal processing. Journal of Agricultural and Food Chemistry. 2005;53(11):4403–4409. PMID 15913302
  4. U.S. Food and Drug Administration. Talking About Juice Safety: What You Need to Know. fda.gov
  5. U.S. Food and Drug Administration. Juice HACCP. fda.gov
  6. Millard PS, Gensheimer KF, Addiss DG, et al. An outbreak of cryptosporidiosis from fresh-pressed apple cider. JAMA. 1994;272(20):1592–1596. PMID 7966869
  7. Muraki I, Imamura F, Manson JE, et al. Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies. BMJ. 2013;347:f5001. PMID 23990623
  8. Heyman MB, Abrams SA; Section on Gastroenterology, Hepatology, and Nutrition; Committee on Nutrition. Fruit Juice in Infants, Children, and Adolescents: Current Recommendations. Pediatrics. 2017;139(6):e20170967. PMID 28562300

Last updated: October 6, 2026